Effective translation of biotechnology research into practical applications requires early and systematic integration of regulatory considerations within research design and implementation. However, many research proposals fail to adequately address regulatory requirements, leading to delays, increased costs, and reduced feasibility in later stages of product development. This webinar is designed to support applicants to the ICGEB Collaborative Research Programme (CRP) Ref: and related initiatives by strengthening their policy and regulatory clarity relevant to biotechnology research and commercialisation in East Africa. The session will focus on key regulatory instruments, including biosafety requirements, policy environment, institutional approvals, and the cost implications of compliance. Participants will gain practical insights into how regulatory considerations influence project timelines, budgeting, and feasibility, particularly for research targeting pre-product development stages. The webinar will also highlight common gaps observed in research proposals and guide the integration of regulatory analysis into proposal development. Through a structured presentation and interactive engagement, the session aims to enhance researchers’ capacity to design proposals that are not only scientifically robust but also regulatory-aware and aligned with national and regional requirements. This will ultimately foster successful project implementation and translation of research outputs into tangible innovations.